| Reason, n (%) | Nonanxious Depression N = 1331 | Anxious Depression N = 1299 | p-value |
| Completed | 980 (73.6) | 927 (71.4) | 0.193 |
| Discontinued any reason | 351 (26.4) | 372 (28.6) | |
| Adverse event | 104 (7.8) | 98 (7.5) | |
| Subject decision | 80 (6.0) | 87 (6.7) | |
| Lost to follow up | 80 (6.0) | 69 (5.3) | |
| Lack of efficacy | 59 (4.4) | 69 (5.3) | |
| Protocol violation | 21 (1.6) | 29 (2.2) | |
| Physician decision | 4 (0.3) | 13 (1.0) | |
| Sponsor decision | 2 (0.2) | 4 (0.3) | |
| Other | 1 (0.1) | 1 (0.1) | |
| Death | 0 | 2 (0.2) |